For instance, Weiss himself has been on a low-carb high-fat diet for more than six months, and claims he does feel much better. But he’s clear about what he knows and what he doesn’t. He’s lost weight and his borderline pre-diabetes is gone. Frederick Hecht, MD, research director of the UCSF Osher Center for Integrative Medicine, also is performing more trials aimed at people with type 2 diabetes. In the controlled trials, a ketogenic state has shown promise in improving human glucose control and decreasing the need for diabetes medications.